Latest PUBLICATIONS

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• Seasonal plasma profiles of testosterone and androstenedione in the Gentile di Puglia ram in southern Italy.

  Publication Date: 01/06/1985, on Journal of endocrinological investigation

  by Dell'Aquila S, Crasto A, Alberico G, Varriale B, Pelosi A, Pierantoni R

  DOI: 10.1007/BF03348490

  Seasonal plasma testosterone and androstenedione levels were determined by radioimmunoassay in the Gentile di Puglia ram. Androstenedione remains steady throughout the years, while testosterone shows seasonal changes. Testosterone is at high levels in winter, spring and summer and drops to a low concentration in autumn.

• Isolation and characterization of dipeptidyl peptidase IV from human meconium. Functional role of beta-casomorphins.

  Publication Date: 20/05/1985, on FEBS letters

  by Caporale C, Fontanella A, Petrilli P, Pucci P, Molinaro MF, Picone D, Auricchio S

  DOI:

  Dipeptidyl aminopeptidase IV (DAP-IV) (EC 3.4.14.1) was purified from meconium particles sedimenting at 105 000 X g. Its molecular properties and activity on synthetic and natural substrates (casomorphin and procasomorphin) were investigated.

• Effect of temperature and darkness on testosterone concentration in the testes of intact frogs (Rana esculenta) treated with gonadotrophin-releasing hormone analog (HOE 766).

  Publication Date: 01/04/1985, on General and comparative endocrinology

  by Pierantoni R, Minucci S, Di Matteo L, Fasano S, Varriale B, Chieffi G

  DOI:

  Testicular testosterone was determined by radioimmunoassay in the frog (Rana esculenta) kept in total darkness, at a high or a low temperature (24 or 4 degrees C), and treated with a gonadotrophin-releasing hormone analog (GnRHa, HOE 766). Prolonged exposure to dark conditions seemed to inhibit hypotalamic functions. Moreover, it is shown that high temperature interacts positively with GnRHa treatment on testicular testosterone concentration.

• Stimulatory effect of a GnRH agonist (buserelin) in in vitro and in vivo testosterone production by the frog (Rana esculenta) testis.

  Publication Date: 01/12/1984, on Molecular and cellular endocrinology

  by Pierantoni R, Fasano S, Di Matteo L, Minucci S, Varriale B, Chieffi G

  DOI:

  The summary testicular effects of an agonistic analogue of gonadotropin-releasing hormone (buserelin, GnRHa) have been studied in vitro and in vivo in the frog, Rana esculenta. During 3 h incubation GnRHa (8 X 10(-7) M) potentiated pituitary factors in stimulating testosterone production by minced testes in vitro. After 6 h of incubation 8 X 10(-7) M GnRHa stimulated maximal testosterone output. Testes of 10-day hypophysectomized animals did not show any GnRHa effect in vitro. In vivo, a direct effect of GnRHa on testicular testosterone production was demonstrated in hypophysectomized animals, although this effect was temperature-dependent, requiring the frog to be maintained at a high temperature (24 degrees C). No effect of GnRHa was detectable in frogs kept at a low temperature (4 degrees C).

• Origin of axoplasmic RNA in the squid giant fiber.

  Publication Date: 01/12/1983, on Neurochemical research

  by Cutillo V, Montagnese P, Gremo F, Casola L, Giuditta A

  DOI:

  The origin of axoplasmic RNA in the squid giant fiber was investigated after exposure of the giant axon or of the giant fiber lobe to [3H]uridine. The occurrence of a local process of synthesis was indicated by the accumulation of labeled axoplasmic RNA in isolated axons incubated with the radioactive precursor. Similar results were obtained in vivo after injection of [3H]uridine near the stellate nerve at a sizable distance from the ganglion. Exposure of the giant fiber lobe to [3H]uridine under in vivo and in vitro conditions was followed by the appearance of labeled RNA in the axoplasm and in the axonal sheath. While the latter process is attributed to incorporation of precursor by sheath cells, a sizable fraction of the radioactive RNA accumulating in the axoplasmic is likely to originate from neuronal perikarya by a process of axonal transport.

• Brain protein and DNA synthesis during seizures.

  Publication Date: 01/01/1983, on Advances in neurology

  by Giuditta A, Metafora S, Popoli M, Perrone-Capano C

  DOI:

• Clinical and computerized tomographic study of a case of Schilder's disease.

  Publication Date: 01/02/1982, on Acta neurologica

  by Barbieri F, Filla A, Grossi D, Orefice G, Perretti A, Cirillo S, Buscaino GA

  DOI:

• DNA turnover in rat cerebral cortex.

  Publication Date: 01/01/1982, on Journal of neurochemistry

  by Perrone-Capano C, D'Onofrio G, Giuditta A

  DOI:

  After the intracranial injection of [methyl-3H]thymidine the specific activity of rat cortical DNA increases rapidly, reaching a maximum at about 5 h. More than half of the radioactive DNA disappears from the tissue in the following few hours. During the same period of time the concentration of radioactive DNA in liver remains essentially constant. Minor variations occur in both organs after 41 h. An apparent rapid turnover of DNA is also present in a fraction of purified neuronal perikarya prepared from the cerebral cortex.

• [L-dopa-resistant parkinsonism with cerebral atrophy: striato-nigral degeneration? 2 cases].

  Publication Date: 01/02/1981, on Acta neurologica

  by Dell'Aria V, Ciannella L, Melone MA

  DOI:

• [L-dopa-resistant Parkinson's disease with cerebral atrophy: striato-nigral degeneration?].

  Publication Date: 01/01/1981, on Acta neurologica. Quaderni

  by Dell'Aria V, Ciannella L, Melone MA

  DOI:

• [Some aspects of hysteria: a clinical study].

  Publication Date: 01/01/1979, on Acta neurologica. Quaderni

  by Brandonisio A, Melone MA, Valiani R

  DOI:

• [Preliminary results of isolation and identification of rat sarcolemma and the effect of denervation on membrane-bound neuraminidase activity].

  Publication Date: 01/01/1979, on Acta neurologica. Quaderni

  by Monsurrò MR, Cotrufo R, Melone MA, Metafora S, Felsani A, Prisco PP, Del Rio A, Tajana GF

  DOI:

• [An unusual case of poisoning due to dithiocarbamates with serious neurological symptoms. Analogy with poisoning due to organo-phosphate substances].

  Publication Date: 01/01/1979, on Acta neurologica. Quaderni

  by Melone MA, Brandonisio A, Valiani R, Sepe O

  DOI:

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