Renata Conforti

Researcher of Neuroradiology

Name Renata
Surname Conforti
Institution Università degli Studi della Campania Luigi Vanvitelli
Telephone +39 081 2545575
Address Neuroradiology Unit, Department of Clinical and Experimental Medicine and Surgery, Università della Campania Studi Vanvitelli, Naples, Italy
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Renata Conforti


  • Widespread microstructural white matter involvement in amyotrophic lateral sclerosis: a whole-brain DTI study.

    Publication Date: 01/06/2012 on AJNR. American journal of neuroradiology
    by Cirillo M, Esposito F, Tedeschi G, Caiazzo G, Sagnelli A, Piccirillo G, Conforti R, Tortora F, Monsurrò MR, Cirillo S, Trojsi F
    DOI: 10.3174/ajnr.A2918

    The extensive application of advanced MR imaging techniques to the study of ALS has undoubtedly improved our knowledge of disease pathophysiology, even if the actual spread of the neurodegenerative process throughout the central nervous system is not fully understood. The present study aimed to detect WM patterns of microstructural abnormalities to better investigate the pathologic process in ALS, within but also beyond CSTs, in a whole-brain analysis.

  • Cervical chordoma. A case report and differential diagnosis.

    Publication Date: 01/05/2012 on The neuroradiology journal
    by Conforti R, Taglialatela G, Rinaldi F, Quaranta E, Cirillo M, Paolisso G
    DOI: 10.1177/197140091202500205

    Chordomas are rare and aggressive tumors derived from notochordal remnants, usually arising in the axial skeleton. The most frequently reported anatomic distribution of chordoma is 50% sacral, 35% spheno-occipital and 15% spinal. We describe the case of an elderly lady presenting with progressive dysphagia, headache and neck pain. We found an expansile mass extending from C1 to C3. While running the diagnostic plan we considered a variety of lesions possibly involving the cervical spine. Biopsy revealed the mass was a chordoma.

  • Role of Magnetic Resonance Imaging in Duane's Retraction Syndrome: Presence of the Abducens Nerve Depending on Type. A Clinical-Anatomical Study.

    Publication Date: 01/12/2010 on The neuroradiology journal
    by Taglialatela G, Conforti R, Notaro M, Cotticelli L, Caranci F, Cirillo S
    DOI: 10.1177/197140091002300610

    This study correlated anatomical findings and clinical evidence in Duane's Retraction Syndrome using brain MRI. The study included 11 patients with different types of Duane's Retraction Syndrome (DRS). Each patient underwent brain MRI. The VI(th) nerve was absent in all patients with DRS-I, present in all patients with DRS-II, while findings varied in patients with DRS-III. Our study confirms the literature on the usefulness of brain MRI in diagnosis of Duane's Retraction Syndrome in children.

  • Spontaneous resolution of eosinophilic granuloma in a patient with a psychotic disorder.

    Publication Date: 01/09/2010 on The neuroradiology journal
    by Conforti R, Porto A, Cirillo M, Sgambato A, Galderisi S, Cirillo S
    DOI: 10.1177/197140091002300412

    A 16-year-old female who manifested psychotic symptoms underwent CT and MRI for the evaluation of an incidentally discovered asymptomatic palpable mass of the right occipital region of the skull. The correlation between clinical and radiological data and biopsy data led to the diagnosis of eosinophilic granuloma. The radiological finding is discussed and reviewed in relation to clinical aspects and literature data.

  • Hippocampal asymmetry with hippocampal sulcus remnants in a patient with mild cognitive impairment. A case report.

    Publication Date: 01/09/2010 on The neuroradiology journal
    by Conforti R, Ronza FM, Di Costanzo A, De Cristofaro M, Cirillo M, Cirillo S
    DOI: 10.1177/197140091002300402

    A 65-year-old woman underwent MRI for a mild cognitive impairment (MCI) at Mini-Mental State Examination (MMSE). MRI showed hippocampal sulcus remnants bilaterally, although they were larger on the right, and left hippocampal atrophy with increased left fimbriosubicular distance (right side: 1.2 mm; left side: 2.0 mm). The meaning of these findings in relation to clinical aspects is discussed and reviewed according to data from the literature.

  • Non-Alcoholic Wernicke Encephalopathy: MR Imaging and Review of the Literature.

    Publication Date: 01/04/2010 on The neuroradiology journal
    by Saturnino PP, Conforti R, Amoroso V, D'Agostino V, Ferrara M, Cirillo S
    DOI: 10.1177/197140091002300202

    We describe a patient with non-alcoholic Wernicke's encephalopathy caused by long-term parenteral nutrition. The diagnosis is based on clinical and magnetic resonance findings. We also reviewed the literature review in typical and atypical findings at MR examination.

  • Lung cancer single intramedullary metastasis vs delayed radionecrosis. A case report.

    Publication Date: 29/08/2009 on The neuroradiology journal
    by Conforti R, Tagliatatela G, De Cristoforo M, Di Costanzo A, Scuotto A, Sanpaolo S, Dericoloso A, Cirillo S
    DOI: 10.1177/197140090902200417

    Intramedullary metastases are rare, accounting for 0.9-5% of spinal metastases. Radiation myelopathy is considered one of the most distressing complications of radiotherapy. In both cases symptoms are aspecific, and there are no characteristic neuroradiologic findings. We describe a case of single intramedullary metastasis from lung microcytoma in a 55-year-old man with a history of malignancy, treated by radiotherapy five years previously. The patient returned to our observation complaining of pain and paraesthesia in the left C7 area. Spinal MRI and rachicentesis findings were aspecific. Ten days later a new MRI showed that the lesion size had increased, and neoplastic cells were found in CSF. Intramedullary metastases are extremely rare, accounting for 0.1-0.4% of all CNS tumors. The risk of developing delayed radionecrosis varies with the total dose administered. In both cases diagnosis is histological, while contrast-enhanced MRI is highly sensitive and specific in identifying and characterizing the lesion. In case of metastatic lesions the prognosis is unfavorable. Differential diagnosis is important because it has a strong effect on patient management.

  • Problem in diagnostic radiology.

    Publication Date: 01/03/2008 on Clinical anatomy (New York, N.Y.)
    by Conforti R, Taglialatela G, Dinacci D, Scuotto A, Tedeschi G, Cirillo S
    DOI: 10.1002/ca.20582

    The case of a 58-year-old woman is described. She presented with what initially seemed to be a transient ischaemic attack. Clinical imaging, however,revealed an intracranial lipoma of the cisterna magna associated with a defect of the occipital bone and spina bifida occulta of the atlas.

  • Infratentorial progressive multifocal leukoencephalopathy in a patient treated with fludarabine and rituximab.

    Publication Date: 01/02/2008 on Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
    by Bonavita S, Conforti R, Russo A, Sacco R, Tessitore A, Gallo A, Della Corte M, Monsurrò MR, Tedeschi G
    DOI: 10.1007/s10072-008-0857-x

    Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the central nervous system caused by the JC papovavirus, and is a well known complication in patients with lymphoproliferative diseases (LPDs) during chemotherapy. We report the case of a 59-year-old woman affected by B-cell LPD who underwent three cycles of chemotherapy with fludarabine and rituximab and developed atypical PML six months after the last cycle of chemotherapy. Our patient showed the following peculiarities: chemotherapy regimen was neither heavy nor prolonged; the onset of neurological symptoms was unexpectedly late; the MRI lesion was atypical for non-HIV-related PML, being monofocal and infratentorial with early gadolinium (Gd) enhancement and mass effect; survival was rather prolonged despite the lack of treatment. These data suggest that in patients with LPDs, the occurrence of progressive neurological deficits should induce the suspicion of PML even when clinical onset is late (with respect to chemotherapy) and in the presence of a single infratentorial lesion, with Gd enhancement and mass effect.

  • A rare symptomatic presentation of ecchordosis physaliphora: neuroradiological and surgical management.

    Publication Date: 01/06/2007 on Journal of neurology, neurosurgery, and psychiatry
    by Rotondo M, Natale M, Mirone G, Cirillo M, Conforti R, Scuotto A
    DOI: 10.1136/jnnp.2006.109561

    We report a case of ecchordosis physaliphora, an uncommon benign lesion originating from embryonic notochordal remnants, intradurally located in the prepontine cistern, that unusually presented associated with symptoms. MRI detected and precisely located the small mass. At surgery, a cystic gelatinous nodule was found ventral to the pons, contiguous with the dorsal wall of the clivus via a small pedicle. Histological examination diagnosed the lesion as an ecchordosis physaliphora. Here we focus on the analysis of the neuroradiological aspects that play a crucial role from both a diagnostic and a therapeutic standpoint.