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Marina Melone
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Affiliazione : Università degli Studi della Campania Luigi Vanvitelli
Profilo Ricercatore
Marina Melone
Neurologa
"Borderline" idiopathic CD4+ T-cell lymphocytopenia presenting with atypical progressive multifocal leukoencephalopathy
Diffuse glioblastoma resembling acute hemorrhagic leukoencephalitis
Short and long term effects of Nabiximols on balance and walking assessed by 3D-gait analysis in people with Multiple Sclerosis and spasticity
Palliative Care for Children and Adults With Inherited Metabolic Disease in Europe: An Underutilised Service for Supportive Treatment and Care.
HPDL Biallelic Variants in Cerebral Palsy and Childhood-Onset Hereditary Spastic Paraplegia: Human and Zebrafish Insights.
Serum miRNAs as biomarkers in Neurofibromatosis 1: New promising findings.
Clinical Efficacy of Selumetinib in Alleviating Neuropathic Pain Associated with Plexiform Neurofibroma: A Case Series
Postural Abnormalities on the Sagittal Plane in Parkinson’s Disease and Therapeutic Role of the K1 Posture Keeper Shirt Evaluated by 3D Motion Analysis
Human blood lipid profiles after dietary supplementation of different omega 3 ethyl esters formulations.
Sagittal kinematics and imbalance of the spine and whole body during walking in late-onset Pompe disease
New insights into the molecular basis of spinal neurofibromatosis type 1
A Translational Approach to Spinal Neurofibromatosis: Clinical and Molecular Insights from a Wide Italian Cohort
Truncated Analogues of a G-Quadruplex-Forming Aptamer Targeting Mutant Huntingtin: Shorter Is Better!
Correction: Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence.
Genotype-Phenotype Correlations in Neurofibromatosis Type 1: Identification of Novel and Recurrent NF1 Gene Variants and Correlations with Neurocognitive Phenotype
Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression.
Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies
Clinical-Genetic Features Influencing Disability in Spastic Paraplegia Type 4: A Cross-sectional Study by the Italian DAISY Network.
Nanoparticle-Guided Brain Drug Delivery: Expanding the Therapeutic Approach to Neurodegenerative Diseases
NGS in Hereditary Ataxia: When Rare Becomes Frequent
POLR3A variants in hereditary spastic paraparesis and ataxia: clinical, genetic, and neuroradiological findings in a cohort of Italian patients
Long-term effects of asymmetrical posture in boxing assessed by baropodometry.
Quantitative Evaluation of Upright Posture by x-Ray and 3D Stereophotogrammetry with a New Marker Set Protocol in Late Onset Pompe Disease.
"One Health" Approach for Health Innovation and Active Aging in Campania (Italy).
Diagnostic issues faced by a rare disease healthcare network during Covid-19 outbreak: data from the Campania Rare Disease Registry.
Rare Variants in Autophagy and Non-Autophagy Genes in Late-Onset Pompe Disease: Suggestions of Their Disease-Modifying Role in Two Italian Families
Neuroacanthocytosis Syndromes in an Italian Cohort: Clinical Spectrum, High Genetic Variability and Muscle Involvement
Short and long term effects of Nabiximols on balance and walking assessed by 3D-gait analysis in people with Multiple Sclerosis and spasticity
Novel autophagic vacuolar myopathies: Phenotype and genotype features.
A case of paramyotonia and periodic paralysis associated with an unreported mutation in the CACNA1S gene
Clinical and genetic features of a large cohort of Italian SPG4 patients from the DAISY collaborative network
Expression profiling of circulating miRNA in the Neurofibromatosis type 1 and related cancers in a large NF1 Italian cohort
Neurofibromatosis type 1: Molecular spectrum of the NF1 mutations in a large cohort of adult Italian patients
Quantitative Evaluation of Upright Posture by X-Ray and 3D Stereophotogrammetry With an Original Marker Placement Protocol in Late Onset Pompe Disease.
BIOM-10. PREVALENCE OF NF1 MISSENSE MUTATIONS AND CANDIDATE MODIFIER GENES IN SPINAL NEUROFIBROMATOSIS PATIENTS
Understanding the Biological Activities of Vitamin D in Type 1 Neurofibromatosis: New Insights into Disease Pathogenesis and Therapeutic Design
Anti-VEGF DNA-based aptamers in cancer therapeutics and diagnostics.
The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity
Bioactive Phenolic Compounds in the Modulation of Central and Peripheral Nervous System Cancers: Facts and Misdeeds
A novel mutation of VCP gene is responsible for Autosomal Dominant (AD) Hereditary Spastic paraplegia (HSP) in a family from Southern Italy
Identification of seven novel mutations in ABCD1 by a DHPLC-based assay in Italian patients with X-linked adrenoleukodystrophy (Retraction of Vol 25, Pg 222, 2005)
Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence
Intrafamilial “DOA-plus” phenotype variability related to different OMI/HTRA2 expression
PREVALENCE OF NF1 MISSENSE MUTATIONS AND CANDIDATE MODIFIER GENES IN SPINAL NEUROFIBROMATOSIS PATIENTS
Silencing of RB1 and RB2/P130 during adipogenesis of bone marrow stromal cells results in dysregulated differentiation (vol 13, pg 482, 2020)
The Autophagy Signaling Pathway: A Potential Multifunctional Therapeutic Target of Curcumin in Neurological and Neuromuscular Diseases
Clinical and Genetic Findings in Children with Neurofibromatosis Type 1, Legius Syndrome, and Other Related Neurocutaneous Disorders
Senescence Phenomena and Metabolic Alteration in Mesenchymal Stromal Cells from a Mouse Model of Rett Syndrome
Metabolic syndrome, Mediterranean diet, and polyphenols: Evidence and perspectives
A rapid, safe, and quantitative in vitro assay for measurement of uracil-DNA glycosylase activity.
Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells
Late adult-onset adrenomyeloneuropathy evolving with atypical severe frontal lobe syndrome: Importance of neuroimaging
Early posterior vitreous detachment is associated with LAMA5 dominant mutation
A case of Foix-Chavany-Marie syndrome due to bilateral corona radiata infarcts
A novel heterozygous SCL52A3 mutation in a case of Brown-Vialetto-Van Laere syndrome with an unusual slowly progressive course
Filamin B and CD13 are components of senescent secretomes that may be involved in primary (stress induced) and paracrine senescence of mesenchymal stromal cells
The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells
Next Generation Molecular Diagnosis of Hereditary Spastic Paraplegias: An Italian Cross-Sectional Study.
Mesenchymal stromal cells from amniotic fluid are less prone to senescence compared to those obtained from bone marrow: An in vitro study
Meldonium improves Huntington’s disease mitochondrial dysfunction by restoring peroxisome proliferator-activated receptor γ coactivator 1α expression
Neurofibromatous neuropathy: An ultrastructural study
Adult‐onset brain tumors and neurodegeneration: Are polyphenols protective?
Nano-delivery systems for encapsulation of dietary polyphenols: An experimental approach for neurodegenerative diseases and brain tumors.
Stress and stem cells: adult Muse cells tolerate extensive genotoxic stimuli better than mesenchymal stromal cells
Migraine as possible red flag of PFO presence in suspected demyelinating disease
Neural stem cells from a mouse model of Rett syndrome are prone to senescence, show reduced capacity to cope with genotoxic stress, and are impaired in the differentiation process
Huntingtin protein: A new option for fixing the Huntington's disease countdown clock.
The role of enhancer of zeste homolog 2: From viral epigenetics to the carcinogenesis of hepatocellular carcinoma
Successful long-term therapy with flecainide in a family with paramyotonia congenita.
The carnitine system and cancer metabolic plasticity.
Verapamil Inhibits Ser202/Thr205 Phosphorylation of Tau by Blocking TXNIP/ROS/p38 MAPK Pathway.
ARE MITOCHONDRIA A POSSIBLE THERAPEUTIC TARGET IN HUNTINGTON'S DISEASE?
Neuro-Behçet’s disease presenting as an isolated progressive cognitive and behavioral syndrome
Autosomal dominant myopia associated to a novel P4HA2 missense variant and defective collagen hydroxylation.
Magnetic Resonance Imaging correlates of benign and malignant alterations of the spinal bone marrow.
Vacuolated PAS-positive lymphocytes as an hallmark of Pompe disease and other myopathies related to impaired autophagy.
Localization of neuroglobin in the brain of R6/2 mouse model of Huntington’s disease
Targeted therapy of human glioblastoma via delivery of a toxin through a peptide directed to cell surface nucleolin.
Identification of the first dominant mutation of LAMA5 gene causing a complex multisystem syndrome due to dysfunction of the extracellular matrix.
Synergistic Interplay between Curcumin and Polyphenol-Rich Foods in the Mediterranean Diet: Therapeutic Prospects for Neurofibromatosis 1 Patients.
Resveratrol protects neuronal-like cells expressing mutant Huntingtin from dopamine toxicity by rescuing ATG4-mediated autophagosome formation.
Multiple spinal nerve enlargement and SOS1 mutation: further evidence of overlap between Neurofibromatosis type 1 and Noonan phenotype.
First study on the peptidergic innervation of the brain superior sagittal sinus in humans
Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes
Alterations in the carnitine cycle in a mouse model of Rett syndrome
Alterations in the carnitine cycle in a mouse model of Rett syndrome.
Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes.
Postural and gait patterns assessed by 3D movement analysis in a late onset Pompe disease sibship
Huntingtin polyQ Mutation Impairs the 17β-Estradiol/Neuroglobin Pathway Devoted to Neuron Survival.
Correction: Systemic Delivery of Recombinant Brain Derived Neurotrophic Factor (BDNF) in the R6/2 Mouse Model of Huntington's Disease.
Dopamine exacerbates mutant Huntingtin toxicity via oxidative-mediated inhibition of autophagy in SH-SY5Y neuroblastoma cells: Beneficial effects of anti-oxidant therapeutics.
Rasagiline for sleep disorders in patients with Parkinson's disease: a prospective observational study
The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.
Correction: Systemic delivery of recombinant brain derived neurotrophic factor (BDNF) in the R6/2 mouse model of Huntington's disease (PLoS ONE (2013) 8: 5 (e64037) DOI: 10.1371/journal.pone.0064037)
DOPAMINE IMBALANCE IN HUNTINGTON'S DISEASE: WHEN THE INHIBITION OF AUTOPHAGY CAN LEAD TO CELL CATASTROPHE
Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells
Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells.
A novel diagnostic method to detect truncated neurofibromin in Neurofibromatosis 1.
A novel diagnostic method to detect truncated neurofibromin in neurofibromatosis 1
Ruta graveolens L. induces death of glioblastoma cells and neural progenitors, but not of neurons, via ERK 1/2 and AKT activation
Unusual Stüve-Wiedemann syndrome with complete maternal chromosome 5 isodisomy.
Foix-chavany-marie syndrome in a 17-year-old female with congenital cytomegalovirus infection
Giant thrombosed intracavernous carotid artery aneurysm presenting as Tolosa-Hunt syndrome in a patient harboring a new pathogenic neurofibromatosis type 1 mutation: A case report and review of the literature
High grade glioblastoma is associated with aberrant expression of ZFP57, a protein involved in gene imprinting, and of CPT1A and CPT1C that regulate fatty acid metabolism
Protective effects of modified Mediterranean diet in patients with Parkinson's disease
Rasagiline improves sleep disorders in Parkinson's disease
Silencing of RB1 and RB2/P130 during adipogenesis of bone marrow stromal cells results in dysregulated differentiation
Reasons driving treatment modification in Parkinson's disease: results from the cross-sectional phase of the REASON study.
Adherence to anti-Parkinson drug therapy in the "REASON" sample of Italian patients with Parkinson's disease: the linguistic validation of the Italian version of the "Morisky Medical Adherence Scale-8 items".
A novel KIF5A....fulltext
Efficient cultivation of neural stem cells with controlled delivery of FGF-2
Mutant huntingtin regulates EGF receptor fate in non-neuronal cells lacking wild-type protein
Phosphodiesterase 10A (PDE10A) localization in the R6/2 mouse model of Huntington's disease
Systemic Delivery of Recombinant Brain Derived Neurotrophic Factor (BDNF) in the R6/2 Mouse Model of Huntington's Disease
The ADAMTS18 gene is responsible for autosomal recessive early onset severe retinal dystrophy
A synthetic amino acid substitution of Tyr10 in Aβ peptide sequence yields a dominant negative variant in amyloidogenesis
Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition
Immunohistochemical localization of receptor for advanced glycation end (RAGE) products in the R6/2 mouse model of Huntington's disease
Reduced expression of MECP2 affects cell commitment and maintenance in neurons by triggering senescence: New perspective for Rett syndrome
Changes in the expression of the striatal-enriched protein tyrosine phosphatase and of extracellular regulated kinase in the R6/2 mouse model of Huntington's disease
Controlled delivery of the heparan sulfate/FGF-2 complex by a polyelectrolyte scaffold promotes maximal hMSC proliferation and differentiation
RAGE-TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion
Genes involved in regulation of stem cell properties: studies on their expression in a small cohort of neuroblastoma patients
Identification of novel mutations in the SLC25A15 gene in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome: a clinical, molecular, and functional study
Identification of novel mutations in the SLC25A15 Gene in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome: A clinical, molecular, and functional study
Screening of ARHSP-TCC patients expands the spectrum of SPG11 mutations and includes a large scale gene deletion
New Targets for Therapy in Polyglutamine (polyQ) Expansion Diseases
A novel KIF5A/SPG10 mutation in spastic paraplegia associated with axonal neuropathy
RAGE recycles at the plasma membrane in S100B secretory vesicles and promotes Schwann cells morphological changes
Neurofibromatosis type 1 and optic pathway glioma. A long-term follow-up.
Brg1 chromatin remodelling factor is involved in cell growth arrest, apoptosis and senescence of rat mesenchymal stem cells
Muscle tissue engineering: Strategies for repair and regeneration in human degenerative muscle diseases
Neuroblastoma in a pediatric era: Specific gene expression of staminality
RB and RB2/P130 genes cooperate with extrinsic signals to promote differentiation of rat neural stem cells
A comparative analysis of different biomaterials in the engineering of skeletal muscle using C2C12 cells in vitro
Spastic paraplegia with thin corpus callosum: Description of 20 new families, refinement of the SPG11 locus, candidate gene analysis and evidence of genetic heterogeneity
Autosomal dominant hereditary spastic paraplegia: DHPLC-based mutation analysis of SPG4 reveals eleven novel mutations.
Identification of seven novel mutations in ABCD1 by a DHPLC-based assay in Italian patients with X-linked adrenoleukodystrophy
Differential carnitine/acylcarnitine translocase expression defines distinct metabolic signatures in skeletal muscle cells
Huntington's disease: New frontiers for molecular and cell therapy
Molecular pathways involved in neural in vitro differentiation of marrow stromal stem cells
Neuroacanthocytosis: New developments in a neglected group of dementing disorders
RB and RB2/p130 genes demonstrate both specific and overlapping functions during the early steps of in vitro neural differentiation of marrow stromal stem cells
tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1
Revelation of a New Mitochondrial DNA Mutation (G12147A) in a MELAS/MERFF Phenotype
Role of RB and RB2/P130 genes in marrow stromal stem cells plasticity
Substrates for Transglutaminase Catalyzed Cross-Linking: Relevance to Pathogenesis of Huntington’s Disease and Chorea-Acanthocytosis
Charcot-Marie-Tooth disease with giant axons: a clinicopathological and genetic entity.
EGF-responsive rat neural stem cells: Molecular follow-up of neuron and astrocyte differentiation in vitro
Skeletal muscle metabolism in physiology and in cancer disease
Abnormal accumulation of tTGase products in muscle and erythrocytes of chorea-acanthocytosis patients.
Decreased mitochondrial carnitine translocase in skeletal muscles impairs utilization of fatty acids in insulin-resistant patients.
Decreased mitochondrial carnitine translocase in skeletal muscles impairs utilization of fatty acids in insulin-resistant patients
Carnitine protects the molecular chaperone activity of lens alpha-crystallin and decreases the post-translational protein modifications induced by oxidative stress.
Carnitine protects the molecular chaperone activity of lens α-crystallin and decreases the post-translational protein modifications induced by oxidative stress
17-β estradiol elicits an autocrine leiomyoma cell proliferation: Evidence for a stimulation of protein kinase-dependent pathway
A new tRNAHis mutation in the mtDNA results in mitochondrial encephalomyopathy by hampering ATP production
pRb2/p130 gene overexpression induces astrocyte differentiation
RB2/p130 ectopic gene expression in neuroblastoma stem cells: evidence of cell-fate restriction and induction of differentiation
RB2/p130 ectopic gene expression in neuroblastoma stem cells: Evidence of cell-fate restriction and induction of differentiation
Biochemical and morphological evidences supporting the hypothesis of a role of TGase in the pathogenesis of chorea acanthocytosis (C-A)
Defective growth in vitro of duchenne muscular dystrophy myoblasts: The molecular and biochemical basis
Increased expression of IGF-binding protein-5 in Duchenne Muscular Dystrophy (DMD) fibroblasts correlates with the fibroblast-induced downregulation of DMD myoblast growth: An in vitro analysis
Increased transcription of IGF binding protein-5 (IGFBP-5) mRNAs in duchenne muscular dystrophy (DMD) fibroblasts correlates with the fibroblast induced downregulation of DMD myoblast proliferation: An in vitro analysis
Induction of apoptosis in ovarian carcinoma cells by AHPN/CD437 is mediated by retinoic acid receptors
Defective growth in vitro of Duchenne muscular dystrophy myoblasts: The molecular and biochemical basis
Induction of apoptosis and differentiation in neuroblastoma and astrocytoma cells by the overexpression of Bin1, a novel Myc interacting protein.
Antisense inhibitory effect: a comparison between 3'-partial and full phosphorothioate antisense oligonucleotides.
Antisense inhibitory effect: A comparison between 3'-partial and full phosphorothioate antisense oligonucleotides
Differentiation and apoptosis of neuroblastoma cells: Role of N-myc gene product
Induction of apoptosis and differentiation in neuroblastoma and astrocytoma cells by the overexpression of Bin1, a novel Myc interacting protein
Modulation of in vitro myogenesis induced by different polymer substrates
Antisense oligonucleotides and myotonin gene expression in C2 mouse cells.
Neurofibromatosis type 1 in children: 10 years of experience
Neurofibromatosis type 1 in children: 10 years of experience
Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: A possible mechanism contributing to CAG-triplet diseases
MRI 'fogging' in cerebellar ischaemia: Case report
The differential effects of poly(2-hydroxyethyl methacrylate) and poly(2-hydroxyethyl methacrylate)/poly(caprolactone) polymers on cell proliferation and collagen synthesis by human lung fibroblasts
Cell-biomaterial interactions: Role of transglutaminase enzyme
Modulation of cytokine production in activated human monocytes by somatostatin
Myotonic dystrophy: Antisense oligonucleotide inhibition of DMPK gene expression in vitro
Functional and structural recovery of myotubes from mice with muscular dysgenesis after co-culture with normal, non-myoblastic cells
NEUROSYPHILIS AND HALLEVORDEN-SPATZ DISEASE - A CLINICAL CASE-REPORT
[Phosphorus NMR spectroscopy. Its value in the diagnosis of metabolic myopathies. A case of Mac Ardle's disease].
PHOSPHORUS NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY IN THE DIAGNOSIS OF METABOLIC MYOPATHY - APPLICATION IN A NEW CASE OF MCARDLE DISEASE
Regenerated EDL muscle of rats requires innervation to maintain AChE molecular forms
Effects of glycyl-L-glutamine in vitro on the molecular forms of acetylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat.
Distributions of molecular forms of acetylcholinesterase and butyrylcholinesterase in nervous tissue of the cat.
Acetylcholinesterase in neuroblastoma and neuroblastoma × glioma hybrid cells: Cellular localization and molecular forms
Phenotype heterogeneity among hemizygotes in a family biochemically screened for adrenoleukodystrophy
CELLULAR-LOCALIZATION AND MOLECULAR-FORMS OF ACHE IN NEURO-BLASTOMA CULTURE
Scanning electron microscopic study of nerve-muscle junctions in embryonic rat cell cultures.
SCANNING ELECTRON-MICROSCOPIC STUDY OF NERVE-MUSCLE JUNCTIONS IN EMBRYONIC RAT-CELL CULTURES
Establishment of neuromuscular contacts in cultures of rat embryonic cells: Effect of tetrodotoxin on maturation of muscle fibers and on formation and maintenance of acetylcholinesterase and acetylcholine receptor clusters
Establishment of neuromuscular contacts in cultures of rat embryonic cells: effect of tetrodotoxin on maturation of muscle fibers and on formation and maintenance of acetylcholinesterase and acetylcholine receptor clusters.
[L-dopa-resistant parkinsonism with cerebral atrophy: striato-nigral degeneration? 2 cases]
[L-dopa-resistant Parkinson's disease with cerebral atrophy: striato-nigral degeneration?]
CONGENITAL CEREBELLAR-ATAXIA, SECTORAL TAPETORETINAL DEGENERATION AND MENTAL-RETARDATION OBSERVED IN 2 SIBLINGS
COMBINED CULTURES OF MUSCULAR AND NEURAL CELLS - STUDY BY SCANNING ELECTRON-MICROSCOPY
[An unusual case of poisoning due to dithiocarbamates with serious neurological symptoms. Analogy with poisoning due to organo-phosphate substances]
[Preliminary results of isolation and identification of rat sarcolemma and the effect of denervation on membrane-bound neuraminidase activity]
[Some aspects of hysteria: a clinical study]
NEURAL CONTROL OF GENE-EXPRESSION OF SKELETAL-MUSCLE FIBERS
